3-Bromopyruvate is known for glycolytic inhibitors. Potential target is hexoknase II and/or glyceraldehyde 3-phosphate dehydrogenase (GAPDH).
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In vitro test:
Dissolve in distilled water to make a 0.5 M stock solution. Aliquote and store at -20 degree
1. Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells. Science. 2009; 325:1555. Yun J, Rago C, Cheong I, Pagliarini R, Angenendt P, Rajagopalan H, Schmidt K, Wilson JK, Markowitz S, Zhou S, Diaz LA Jr, Velculescu V, Lengauer C, Kinzler KW, Vogelstein B, Papadopoulos N.
|Eppendorf epMotion 5070|
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|Macherey - Nagel|
|The German brand of DNA and RNA extraction kits since 1911! The world is optimizing NextGen sequencing templates with Macherey-Nagel.|
|Whole Exome Enrichment|
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