3-bromopyruvate (3-BrPA)

WFID: 10096   Date: 06-19-2011  
Protocol Format: Public Draft.
Jihye Yun  
Tissueculture,
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Introduction

3-Bromopyruvate is known for glycolytic inhibitors. Potential target is hexoknase II and/or glyceraldehyde 3-phosphate dehydrogenase (GAPDH).

Materials

Catalog # Material Name Company Name Solute/Solvent
1238341-5GBromopyruvic acidsgimaSolute

Protocol

In vitro test:
Dissolve in distilled water to make a 0.5 M stock solution. Aliquote and store at -20 degree

Attachments

References

1. Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells. Science. 2009; 325:1555. Yun J, Rago C, Cheong I, Pagliarini R, Angenendt P, Rajagopalan H, Schmidt K, Wilson JK, Markowitz S, Zhou S, Diaz LA Jr, Velculescu V, Lengauer C, Kinzler KW, Vogelstein B, Papadopoulos N.

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